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Siltuximab Injection (SILTUXIMAB - INJECTION)

For blood cell disorders.

Brand Name(s): Sylvant

Generic Name: Siltuximab

Instructions

This is an IV medicine. It is given through a sterile tube directly into the vein by a healthcare provider.

This medicine is given gradually through the IV line.

This medicine should be given over 60 minutes.

This medicine should be given by a trained health care provider.

You must be monitored by a health care professional during and after each dose is given.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Your doctor may prescribe other medications to reduce side effects. Follow instructions carefully.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Tell doctor or nurse right away if fever, chills, feeling of heat or flushing, coughing, chest pain, dizziness, fainting, headache, nausea or vomiting, itching, swelling of the face or throat, or trouble breathing develop while the medicine is being given. The medicine may need to be stopped or given at a slower rate.

This medicine may reduce your body's ability to fight infections. Avoid contact with people with colds, flu or other infections. Contact your doctor if you develop fever, cough, sore throat, or chills.

Speak with your health care provider before receiving any vaccinations.

Do not breastfeed while on this medicine. You may safely start breastfeeding 3 months after stopping treatment.

This medicine can hurt a new baby in the womb. If you become pregnant while on this medicine, tell your doctor immediately. Your doctor may switch you to a different medicine.

Women must use reliable forms of birth control while taking this medicine and for 3 months after stopping to prevent pregnancy.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • constipation or diarrhea
  • dry skin
  • headaches
  • pain in the joints
  • pain in arms or legs
  • weight gain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • cough that does not go away
  • fever or chills
  • signs of kidney damage (such as change in urine color or bubbly urine)
  • sore throat
  • stomach pain

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

 
 

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