Skip to main content

Benzoyl Peroxide/Tretinoin Topical Cream (TRETINOIN/BENZOYL PEROXIDE - TOPICAL)

For acne.

Brand Name(s): Twyneo

Generic Name: Benzoyl Peroxide/Tretinoin

Instructions

DO NOT take this medicine by mouth.

Gently clean the affected area with a mild, soapless cleanser and pat dry before using this medicine.

Apply a thin layer to the affected area and rub it in.

Keep the medicine at room temperature. Avoid heat and direct light.

This medicine should only be used on the skin.

Do not use any other acne medicines on your skin while using this medicine unless instructed by your doctor.

Avoid getting the medicine in the eyes, nose, or mouth. Wash the medicine off your fingers after applying it.

This medicine may bleach fabric or hair.

Avoid prolonged or excessive sunlight exposure. Use sunscreen lotion with SPF 15 or higher.

Do not use on cuts, scrapes, open wounds, sunburned skin, or skin with eczema (rash).

Wash your hands before and after handling this medicine.

If medicine gets in your eyes, rinse well with cool water.

Use a moisturizing cream or lotion to reduce skin irritation.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Discard this medicine 12 weeks after receiving it, or 30 days after opening, whichever is sooner.

Do not freeze the medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Do not use the medication any more than instructed.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

If you forget to take a dose on time, take it as soon as you remember. If it is almost time for the next dose, do not take the missed dose. Return to your normal schedule. Do not take 2 doses at one time.

Do not share this medicine with anyone who has not been prescribed this medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • burning or stinging
  • dry skin
  • skin irritation where medicine is applied
  • skin redness

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • blistering or peeling of the skin
  • change in skin color

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

 
 

PeaceHealth endeavors to provide comprehensive health care information, however some topics in this database describe services and procedures not offered by our providers or within our facilities because they do not comply with, nor are they condoned by, the ethics policies of our organization.