Phenylephrine-Pheniramine
Drug Information
Summary of Interactions with Vitamins, Herbs, & Foods
Replenish Depleted Nutrients
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none
Reduce Side Effects
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none
Support Medicine
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none
Reduces Effectiveness
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none
Potential Negative Interaction
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none
Explanation Required
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Fo-Ti
Many drugs used in the treatment of high blood pressure cause relaxation or dilation of blood vessels. Laboratory studies show that emodin, a compound in Polygonum multiflorum, also relaxes blood vessels. However, animal studies reveal that phenylephrine blocks the action of emodin. Controlled studies are needed to determine whether Polygonum multiflorum helps people with high blood pressure and whether phenylephrine blocks its beneficial effects.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Last Review: 03-24-2015
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