Chlorpheniram-Pe-Chlophedianol
Drug Information
Summary of Interactions with Vitamins, Herbs, & Foods
Replenish Depleted Nutrients
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none
Reduce Side Effects
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none
Support Medicine
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none
Reduces Effectiveness
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none
Potential Negative Interaction
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Antihistamines, including chlorpheniramine, can cause “anticholinergic” side effects such as dryness of mouth and heart palpitations. Henbane (Hyoscyamus niger) also has anticholinergic activity and side effects. Therefore, use of henbane with chlorpheniramine could increase the risk of anticholinergic side effects, though apparently no interactions have yet been reported. Henbane should not be taken except by prescription from a physician trained in its use, as it is extremely toxic.
The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
Explanation Required
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none
Last Review: 03-24-2015
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