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CPM-PSE-Atropine-Hyosc-Scop

Drug Information

Summary of Interactions with Vitamins, Herbs, & Foods

Types of interactions: Beneficial Adverse Check

Replenish Depleted Nutrients

  • none

Reduce Side Effects

  • none

Support Medicine

  • none

Reduces Effectiveness

  • Tannins are a group of unrelated chemicals that give plants an astringent taste. Herbs containing high amounts of tannins, such as green tea (Camellia sinensis), black tea, uva ursi (Arctostaphylos uva-ursi), black walnut (Juglans nigra),red raspberry (Rubus idaeus),oak (Quercus spp.), and witch hazel (Hamamelis virginiana), may interfere with the absorption of atropine taken by mouth.

    The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

Potential Negative Interaction

  • Iron
    Absorption of ferrous citrate, an iron compound that is usually well absorbed, is reduced in individuals taking hyoscyamine; therefore, these two substances should not be taken at the same time.
  • The herb Anisodus tanguticus contains a chemical that has effects similar to atropine, a compound related to hyoscyamine. Though no human studies have investigated a possible adverse interaction between hyoscyamine and anisodus, individuals should avoid the combination until more is known.

    The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.
  • Antihistamines, including chlorpheniramine, can cause “anticholinergic” side effects such as dryness of mouth and heart palpitations. Henbane (Hyoscyamus niger) also has anticholinergic activity and side effects. Therefore, use of henbane with chlorpheniramine could increase the risk of anticholinergic side effects, though apparently no interactions have yet been reported. Henbane should not be taken except by prescription from a physician trained in its use, as it is extremely toxic.

    The interaction is supported by preliminary, weak, fragmentary, and/or contradictory scientific evidence.

Explanation Required 

  • none

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

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