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Barberry

Uses

Botanical names:
Berberis vulgaris

Parts Used & Where Grown

The root and stem bark contain the medicinally active components of barberry. The barberry bush also produces small red berries. Although this particular species is native to Europe, it now also grows throughout North America. A closely related species, Oregon grape (Berberis aquifolium), is native to North America.

What Are Star Ratings?

This supplement has been used in connection with the following health conditions:

Used for Why
1 Star
Chronic Candidiasis
Refer to label instructions
Barberry contains berberine, an alkaloid with antibiotic activity that also been shown to help relieve the diarrhea seen in some people with chronic candidiasis.

Berberine is an alkaloid found in various plants, including goldenseal, , Oregon grape, and goldthread. Berberine exhibits a broad spectrum of antibiotic and antifungal activity in test tube, animal, and human studies. Berberine has shown effective antidiarrheal activity in a number of diarrheal diseases, and it may offer the same type of relief for the diarrhea seen in patients with chronic candidiasis. Doctors familiar with the use of berberine-containing herbs sometimes recommend taking 2 to 4 grams of the dried root (or bark) or 250 to 500 mg of an herbal extract three times a day. While isolated berberine has been studied, none of these herbs has been studied in humans with chronic candidiasis.

1 Star
Diarrhea
Refer to label instructions
Berberine, a constituent of barbarry, has been shown to improve infectious diarrhea in some double-blind trials.

Due to of its supposed antimicrobial activity, goldenseal has a long history of use for infectious diarrhea. Its major alkaloid, berberine (also found in and Oregon grape), has been shown to improve infectious diarrhea in some double-blind trials. Negative studies have generally focused on people with cholera, while positive studies investigated viral diarrhea or diarrhea due to strains of E. coli. These studies generally used 400–500 mg berberine one to three times per day. Because of the low amount of berberine in most goldenseal products, it is unclear how effective the whole root or root extracts would be in treating diarrhea.

1 Star
Indigestion, Heartburn, and Low Stomach Acidity
Refer to label instructions
Taking barberry may help stimulate digestion and relieve an upset stomach.

Bitter herbs are thought to stimulate digestive function by increasing saliva production and promoting both stomach acid and digestive enzyme production. As a result, they are particularly used when there is low stomach acid but not in heartburn (where too much stomach acid could initially exacerbate the situation). These herbs literally taste bitter. Some examples of bitter herbs include greater celandine, wormwood, gentian,dandelion, blessed thistle, yarrow, devil’s claw, bitter orange, bitter melon, juniper, andrographis, prickly ash, and centaury.. Bitters are generally taken either by mixing 1–3 ml tincture into water and sipping slowly 10–30 minutes before eating, or by making tea, which is also sipped slowly before eating.

Some bitters widely used in traditional medicine in North America include yarrow, yellow dock, goldenseal, Oregon grape, and vervain. Oregon grape’s European cousin has also traditionally been used as a bitter. Animal studies indicate that yarrow, barberry, and Oregon grape, in addition to stimulating digestion like other bitters, may relieve spasms in the intestinal tract.

1 Star
Infection
Refer to label instructions
Barberry is both immune supportive and antimicrobial.

Herbs that support a person’s immune system in the fight against microbes and directly attack microbes include the following: , echinacea, elderberry, goldenseal, licorice, Oregon grape, osha, and wild indigo.

1 Star
Parasites
Refer to label instructions
Berberine is derived from several plants, including barberry. Studies have shown that berberine kills amoebae and can be used successfully to treat giardia infections.

Berberine is derived from several plants, including , Oregon grape, goldenseal, and goldthread (Coptis chinensis). Preliminary trials have shown that berberine can be used successfully to treat giardia infections. In addition, test tube studies show that berberine kills amoebae, although it is not known whether this effect occurs in humans. The amount required is approximately 200 mg three times per day for an adult—a level high enough to potentially cause side effects. Therefore, berberine should not be used without consulting a healthcare provider.

1 Star
Psoriasis
Refer to label instructions
An ointment containing barberry may reduce inflammation and be effective against moderate psoriasis.

An ointment containing Oregon grape (10% concentration) has been shown in a clinical trial to be mildly effective against moderate psoriasis but not more severe cases. Whole Oregon grape extracts were shown in one laboratory study to reduce inflammation often associated with psoriasis. In this study, isolated alkaloids from Oregon grape did not have this effect. This suggests that there are other active ingredients besides alkaloids in Oregon grape. , which is very similar to Oregon grape, is believed to have similar effects. An ointment, 10% of which contains Oregon grape or barberry extract, can be applied topically three times per day.

1 Star
Vaginitis
Refer to label instructions
Barberry is antibacterial and may be effective against infectious vaginitis.

Teas of goldenseal, , and echinacea are also sometimes used to treat infectious vaginitis. Although all three plants are known to be antibacterial in the test tube, the effectiveness of these herbs against vaginal infections has not been tested in humans. The usual approach is to douche with one of these teas twice each day, using 1–2 tablespoons (15–30 grams) of herb per pint of water. One to two pints (500–1,000 ml) are usually enough for each douching session. Echinacea is also known to improve immune function in humans. In order to increase resistance against infection, many doctors recommend oral use of the tincture or alcohol-preserved fresh juice of echinacea (1 teaspoon (5 ml) three or more times per day)—during all types of infection—to improve resistance.

Traditional Use (May Not Be Supported by Scientific Studies)

Traditionally, in European and American herbalism, barberry was used to treat a large number of conditions, particularly infections and stomach problems.1 It has also been used internally to treat skin conditions.

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PeaceHealth endeavors to provide comprehensive health care information, however some topics in this database describe services and procedures not offered by our providers or within our facilities because they do not comply with, nor are they condoned by, the ethics policies of our organization.